Minimal Important Difference in Voice Handicap Index–10

How important is a minimal difference?

C linical trials typically report the mean effect of interventions with an indication of the variability or 95% confidence interval signifying whether an intervention leads to statistically significant effects. A statistical difference does not necessarily inform clinicians or policymakers as to whether patients will perceive these effects as a benefit or whether the effect is of any clinical r...

Comparing the Voice Handicap Index Scores in Groups with Structural and Functional Voice Disorders

Objective: The effects of voice disorders vary from person to person. Occupation, work environment, life, and family reaction are variables that affect one’s perception of his/her own as an impaired voice. Voice Handicap Index (VHI) has not yet been used to compare the degree of voice disorders. Assuming that the quality of life may be different under a variety of voice disorders and that diffe...

The minimal important difference of exercise tests in severe COPD.

Our aim was to determine the minimal important difference (MID) for 6-min walk distance (6MWD) and maximal cycle exercise capacity (MCEC) in patients with severe chronic obstructive pulmonary disease (COPD). 1,218 patients enrolled in the National Emphysema Treatment Trial completed exercise tests before and after 4-6 weeks of pre-trial rehabilitation, and 6 months after randomisation to surger...

Minimal clinically important difference: defining what really matters to patients.

When assessing the clinical utility of therapies intended to improve subjective outcomes, the amount of improvement that is important to patients must be determined.1 The smallest benefit of value to patients is called the minimal clinically important difference (MCID). The MCID is a patient-centered concept, capturing both the magnitude of the improvement and also the value patients place on t...

Minimal clinically important difference module: summary, recommendations, and research agenda.